Applying skin glue is painless. In about 20% of patients there is a report of a sensation of mild heat but no actual pain.1 Wound infection rates are low (less than 3%) and are not increased with skin glues.5
Procedure time is reduced.1,2,5,8 Studies reported that the time of the actual wound repair in all settings was less than formal suturing. Sedation, which is sometimes used in children having sutures, is not needed with skin glues.
Cosmetic appearance with skin glues is comparable to outcomes with sutures and strip approximation.1 Most of the trials have used a blinding method with photographs assessed by plastic surgeons, other doctors and patients themselves. Comparisons were made of appearance, absence of step-off, margin irregularities, separation, edge inversion and wound distortion. The results universally recorded that final cosmetic appearance for skin glues was similar to sutures, and both were better than adhesive strips. 8,9
Skin glues are expensive. However, when compared with equipment and labour costs as well as the need for follow-up for suture removal, the overall cost is felt to be equivalent to sutures.11
Patient satisfaction with skin glues was higher than with sutures in most studies. Reasons included lack of pain, ease of wound care and no need for follow-up and suture removal.
There is no chance of needle-stick injury with skin glues. They provide a barrier for short-term exposure to water. Swimming is generally not recommended.
There are two types of super glue. One is meant for gluing objects and should be kept in your tool box. One is formulated for medical use and should be kept in your first aid kit.
For your tool box:
- Super Glue
- Krazy Glue
For your first aid kit:
2-Octyl-cyanoacrylate
- Dermabond
- SurgiSeal
N-2-butyl-cyanoacrylate
- Histoacryl
- Indermil
- GluStitch
- GluSeal
- LiquiBand
2-Ethyl-cyanoacrylate
- Epiglu
What is super glue?
Super glue uses cyanoacrylate adhesives. Cyanoacrylate adhesives are often referred to as instant adhesives because they don’t have to be mixed with another agent and they cure quickly without heat or curing equipment.
Although cyanoacrylate formulations were tested in World War II for creating plastic gun sights, military medics started using the sticky substance for closing battlefield wounds. It was relatively effective as a quick and waterproof emergency measure, however, there were side effects such as damaging the tissue around the wound and irritating the nose, throat, lungs, and eyes.
Different formulations were tested during the Vietnam War, and in 1998 the U.S. Food and Drug Administration approved a less toxic medical formulation (2-octyl cyanoacrylate) called Dermabond.
Using super glue on cuts
Medical cyanoacrylate adhesives — also called skin glue or surgical glue — are less toxic than the version you keep in your tool box. They also have plasticizers to make them more flexible.
When to use it
The most recommended use for medically approved cyanoacrylate adhesive is to close the two sides of clean minor cuts, such as knife cuts or paper cuts.
In these cases, there are a host of benefits:
- It dries fast to stop the bleeding.
- It stays in place.
- It keeps dirt and air out of the cut.
- By the time it wears off the cut is typically healed.
- It can reduce scarring.
When not to use it
Cyanoacrylate adhesive is not recommended for:
- deep wounds
- jagged wounds
- puncture wounds
- animal bites
- burns
- wounds on the eyes, lips, or genitals
- contaminated wounds
- mobile areas such as joints
- stretched skin areas such as foreheads
Emergency rooms
When appropriate, many hospital emergency departments use surgical glue instead of stitches because:
- It’s faster.
- It’s less painful.
- No needle pokes are necessary.
Follow-up
- It doesn’t need a follow-up visit for suture removal.
- Patients don’t need to be sedated.
- Avoid antibiotic ointments. They will dissolve the dried glue.
- Avoid picking at the edges of the dried glue.
Takeaway
For certain kinds of cuts, super glue can be an effective way of closing the wound for healing. Using the version formulated for medical use — as opposed hardware glue — will avoid irritation and be more flexible. If you have a deep cut that is bleeding profusely, seek professional medical attention.